1. Laboratories used for research in microbiology, biomedicine, biochemistry, animal experiments, gene recombination, and biological products are collectively referred to as biosafety laboratories.

2. The biosafety laboratory consists of a main functional laboratory, other laboratories, and auxiliary functional rooms.

4. Classification of Biosafety Laboratories

5 Technical indicators of biosafety laboratory

explain:

1. The "/" in the table indicates no requirement. The noise in this table does not include the noise of biological safety cabinets and animal isolators. If the noise of the above equipment is included, the maximum should not exceed 68dB (A)

2. The minimum negative pressure of the third level biosafety main laboratory relative to the atmosphere shall not be less than -30Pa, and the minimum negative pressure of the fourth level biosafety main laboratory relative to the atmosphere shall not be less than -50Pa

3. For Level 3 biosafety laboratories that raise animals, the minimum negative pressure relative to the atmosphere must not be less than -50Pa, and for Level 4 biosafety laboratories, the minimum negative pressure relative to the atmosphere must not be less than -60Pa

The construction plan for a biosafety laboratory includes various aspects such as building layout and decoration, air conditioning, water supply and drainage, gas supply, electrical design, centralized control, security, construction technology, testing, and training. In particular, the following aspects of the plan should be fully considered:

1．Architectural layout and decoration plan：It is the foundation for the safe operation of biosafety laboratories. Due to the danger of microbial pathogens, it is necessary to prevent the spread of dangerous microorganisms to the outside world, block the contact pathways between dangerous microorganisms and the external environment, and avoid microbial contamination from the outside, which may affect the accuracy of experimental results. Therefore, a reasonable laboratory layout and decoration plan must be adopted. The laboratory layout is reasonably divided into clean areas, semi polluted areas, and polluted areas according to safety requirements. Special passages are set up for people and objects, necessary buffer rooms are set up, and measures such as primary and secondary isolation are adopted to effectively avoid cross contamination and fundamentally prevent the spread of dangerous microorganisms; The laboratory decoration adopts reliable materials and reasonable construction measures to ensure that the biosafety laboratory is always in a relatively sealed environment, preventing the escape of microorganisms, making it easy to clean the laboratory, and avoiding external damage to the laboratory environment.

2．Air conditioning system：It is the key to the safe operation of biosafety laboratories. Due to the fact that the operating objects in the biosafety laboratory are hazardous microorganisms that pose a risk to human beings, animals, plants, or the environment, it is necessary to maintain a relatively negative pressure environment in the biosafety laboratory through the use of a reasonable air conditioning system at all times to ensure that hazardous microorganisms in the laboratory cannot diffuse into the external environment. The air conditioning system must operate reliably, adopt advanced technology, make reasonable use of and save energy and resources, ensure the quality and safety of the environment, provide the necessary temperature and humidity for experimental personnel, ensure that biological experiments are conducted under safe conditions, and ensure the accuracy of experimental results. At the same time, it must also control the cleanliness of the laboratory and filter the fresh air to meet certain purification requirements. The exhaust system is a key focus, playing an important role in ensuring a relatively negative pressure environment in the laboratory and effectively filtering indoor pollution exhaust.

3．control system：It is the nerve that ensures the safe operation of the entire biosafety laboratory. Due to the fact that the experimental subjects of the biosafety laboratory are hazardous microorganisms, in order to strictly control pollution, it requires minimal maintenance personnel and optimized management and maintenance methods to monitor the physical environment of each equipment in the laboratory in real time, ensuring that the laboratory is always in a relatively negative pressure environment during operation and preventing the leakage of hazardous microorganisms.

4．detection scheme：It is the guarantee for the long-term safe operation of the biosafety laboratory. Due to the particularity of biosafety laboratories, in addition to strict design, construction, and commissioning, necessary engineering testing and strict acceptance must be carried out to ensure their safety. Only after meeting safety and usage requirements can they be put into operation. In addition, some factors during use, such as non professional management and use, replacement of high-efficiency filters, etc., can have an impact on the safety of the laboratory. Therefore, regular testing during use is equally important.

5．training program：Due to the fact that the experimental personnel in biosafety laboratories are usually medical experts, they may not have a complete understanding of the principles of the entire laboratory system. Through training programs, all laboratory staff can understand the characteristics of the entire system, master its operating rules, timely discover safety hazards, and make corresponding emergency responses to control the further deterioration of the situation, which is of great help in reducing the difficulty of subsequent maintenance work.

5. Standardization:The overall biosafety laboratory plan is organized, designed, and constructed by Expansion Technology Company. All plan design, equipment and material procurement, construction project management, and quality supervision services are provided by the company's project design and project management personnel. As the design plan for the overall biosafety laboratory, we hope to achieve standardized design, adopt consistent design concepts, and achieve unified style and quality