Leica LAS X software platform for life science applications-Fornitore globale

Leica LAS X software platform

Targeting life science applications

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The need to use various software for work is a very frustrating thing for researchers, as it makes image analysis complex and tedious.

Leica Application Suite X (LAS X) is a software platform suitable for all Leica microscopes: it integrates Leica's confocal, wide field, stereo, super-resolution, and optical imaging systems.

Users can spend more time on research
Imaging tasks become more intuitive

From basic records to advanced life science research - LAS X can directly guide you to achieve ideal imaging!

The 'North Star' in Image Analysis

LAS X can guide you through the analysis workflow step by step.

Get instant feedback on each step of the application settings through the viewer
Get guidance from the analysis wizard to quickly achieve replicable results
Intuitively obtain 2D and 3D images - facilitating automatic analysis of multiple samples

A major breakthrough in the field of high-speed image acquisition

The high-speed linear electric stage provides precise positioning at unimaginable speeds, such as positioning 5 positions per second under a 40x objective lens. The vibration sensor ensures that the stage is completely stationary during the image acquisition process. The final result is that even with the fastest image acquisition speed, the microscope can capture clear images at the optimal imaging time. The significant improvement in performance comes from optimizing the synchronization between image acquisition and stage movement.

Advantages of Quantum Stage:

High speed positioning with absolute accuracy less than ± 1 µ m
Manually move the stage at any time while maintaining accurate tracking of the slide position

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Smoothly process data

Data auditing and display have become easier:

Select a sample on the screen and then view its highlighted measurement values in the results table
Use automatic classifiers to group and display results
Display and track the trajectory changes of particles over time
Save results and experiments, or create reports containing bar charts and binary masks

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The powerful performance of LAS X in advanced life science research

Complex experiments require rigorous settings and meticulous execution. By emphasizing the comprehensive availability of LAS X, its powerful features are sure to enhance the impact of your research.

High speed image capture
Analyze and review data during image capture, such as FRAP and FRET in LAS X
Use automatic export function for external analysis and feedback to LAS X
Real time creation of excellent 3D rendering timed image capture during the capture process

These zebrafish and fruit fly experimental videos (link to video tab) can give you an understanding of the amazing results that LAS X can achieve even in long-term experiments.

Comprehensive climate control

By using the environmental control module, you can control all environmental data such as temperature, CO2, or O2 conditions in one interface. All data will be saved along with the experiment.

Real time monitoring of environmental data or future review
Run temperature configuration file by using ingestion macro command
When the parameters exceed the range, a warning will be received or the experiment will be automatically stopped

Stay connected!

With the LAS X mobile connectivity module, you can stay connected to your experiments anytime, anywhere.

Start, pause, or stop the experiment, or determine the appropriate time to start the experiment by capturing images, all of which can be done from an iPad or any laptop
Display imaging conditions on your remote device
Download specific images at full resolution and send them to colleagues
Multiple remote users who can connect to the system simultaneously

simplify what is complicated

Even in complex fluorescence experimental analysis, LAS X can easily provide support for you.

Create separate analysis channels for each fluorescent marker or color
Assign independent workflows one by one
Comprehensive analysis of samples can be conducted simultaneously, for example:

Count the spots on each cell nucleus
Counting healthy and abnormal cells in two independent channels

Leica Microsystems, as an innovative microscope manufacturer, has been committed to serving the needs of users to the greatest extent possible since its establishment, developing Leica's high-tech precision systems and micro analysis for users. Leica's product portfolio of microscopy systems includes ultra-high resolution microscopes, optical microscopes, confocal microscopes, surgical microscopes, stereomicroscopes and macroscopic microscopes, digital microscopes, microscope software, microscope cameras, and electron microscope sample preparation. It is widely used not only in biotechnology and medicine, but also in research and development of raw materials and industrial quality assurance.

acquisition module

Module name	Description	wide field	confocal microscopy
LAS X core module	LAS X core software, operation does not require a software decryptor.	x	x
Multi channel acquisition	Up to 8 acquisition channels can be defined for each experiment.	o	x
time series	Define the duration and frequency of image acquisition for time series experiments.	o	x
Z-axis - Control and software autofocus	Focal plane positioning and 3D dataset acquisition. Including software autofocus.	o	x
Tag and search	Determine multiple stage positions and repeat access in time series or Z-axis stack experiments.	o	x
montage	Create an overview image with a large field of view.	o	x
Interview Editor	Conduct porous and multi cavity experiments. Create a custom sample carrier. Automatically assign regions and positions to each hole/cavity.	x	x
Non Leica camera driver program	Can control any third-party camera supported by LAS X.	o	o
extended depth of field	Effectively concatenate the focal area of each image in the 3D series to create a single Extended Depth of Field (EDOF) image.	o	-
Real time image creator	Automatically detect manual sample movement and expand images smoothly without the need to click a button to capture images. Not suitable for fluorescent applications.	o	-
Real time video streaming recording	Record videos directly from a real-time image viewer and store them in AVI format in a user-defined location.	o	-
Peripheral device trigger	Send trigger signals and analog signals to peripheral devices. Incorporate the trigger into the delay experiment. Contains powerful trigger functions, such as sending trigger signals on specific channels or locations.	o	-