virtuecountryMeridionContinuous production spray freeze drying equipment

sprayInnovator of freeze-drying：

GermanyMeridionThe factory is located near Basel in western Germany,Developed and possessed highly innovative spray freeze drying technology, and has beenFocusing on the application of dynamic mass spray drying and freeze-drying microspheres, including the freeze-drying process under normal pressure and vacuum; This is a high-precision team composed of pharmacists, engineers, process technicians, mechanics, and control experts, with decades of experience in pharmaceutical processing equipment and pharmaceutical technology,Provide application laboratory equipment for drug research and development or process certification, as well as project implementation, including engineering, project management, equipment design, manufacturing and installation, start-up, and after-sales service;Provide more optimization in production processes, process technology, and costs.

Spray frozen microsphere

Frozen microspheres are made by using high-precision nozzles to atomize liquid containing samples into tiny droplets. Under the action of gravity, the droplets pass through a cooling zone and instantly solidify into frozen spheres

u Narrow particle size distribution range

u You can choose from 200Mm-800Mm

u After freezing, the product is uniform, has excellent fluidity, and is resistant to contamination

u Product Innovation: After Freeze Drying,Further processing, such as coatings or combination products

advanced technology

◆ Flexible production and cost savings

--Fill in freeze-dried product ingredients as needed

--Fill in the weight of each component as required

--The mixed components are processed by gravity, without the need for traditional freeze dryers that use partition loading and unloading systems

--small bottle/The final collection method is relatively flexible, without the specific requirements of primary packaging for traditional freeze-drying

◆Innovation and flexible formula

--Combining different freeze-dried products to obtain multi-component formulations in the final collection vial, such as overcoming incompatibility

--The product performance can be further improved, especially in solid dosage forms such asExpFor compounds that are not suitable for freeze-drying, rapid release formulations can be obtained using known techniques to date.

Continuous production spray freeze drying equipment

From laboratory scale product development equipment to each batch20For the pharmaceutical production line with a scale of kg, the complete equipment includes a spray freezer and a dynamic freeze drying system. During the freeze drying process, the movable sample cylinder slowly mixes at a constant temperature, and the samples are freeze-dried in a rotating freeze drying system. The energy required for sublimation irradiates the rotating samples through radiation, and controls the temperature of their surfaces.

Save up to50%The drying time

-Maximizing heat exchange (across the entire particle surface)

-Heat is directly transferred to the product

-Maximum steam flow-Unrestricted by partitions

-Promote steam diffusion by reducing the thickness of dried products

Stability of production process

-Directly monitor product related parameters

- reduceOOSresult

-Direct accessPAT

product quality

-Uniform, dust-free, due to fixed and gentle mixing-No clumping, no change in product density

-Directly monitor the temperature of the product